Showing 678 results
Male birth control options are in development, but a number of barriers still stand in the way
A survey of over 9,000 men in nine countries found that over 55% would be willing to use a new method of male birth control.
Tuberculosis kills over a million people a year. New breakthroughs may help humanity fight back.
The world needs a tuberculosis vaccine, but the challenge trials that could help are impossible to run. Two new approaches look to change that.
Magnets pull these tiny medical robots deep into the brain
LA-based startup Bionaut Labs is developing micro-sized medical robots that are guided through the body by magnets.
This already-approved drug could help repair the brain after stroke
Ohio State researchers have found that an already approved anticonvulsant drug helps increase stroke recovery in mice.
New MS treatment targets the gut microbiome
We may be able to prevent chronic inflammation in multiple sclerosis patients by manipulating their gut microbiomes.
This “living medicine” can eliminate a deadly lung infection
Researchers have engineered bacteria to create a “living medicine” against a nasty respiratory bug.
African researchers push for a human challenge trial to fight TB
Tuberculosis kills over a million people a year. Researchers in Malawi are pushing for a clinical trial that may help change that.
A smart bomber for bacteria could help save antibiotics
Brown University researchers have developed a “smart” drug delivery system that only releases its payload when bacteria are present.
A common arthritis drug treats alopecia (Updated)
A common arthritis drug may be an effective alopecia treatment, based on a trial in which it helped people regrow their hair in just 36 weeks.
Nanoparticles are the future of medicine
The success of some drugs that use nanoparticles, such as the COVID-19 mRNA vaccines, has prompted excitement among researchers.
New light therapy could make cancer treatment better and safer
A new light-activated cancer treatment developed in the UK could make existing therapies better and safer.
Engineers develop nanoparticles that cross the blood-brain barrier
Tested using a new brain tissue model, the particles may be able to deliver chemotherapy drugs to cancer patients.
New gel destroys brain cancer in 100% of treated mice
A new brain cancer treatment not only cured 100% of mice that received it, but also trained their immune systems to fight future cancers.
Personalized mRNA vaccine preps the body to battle deadly cancer
A new pancreatic cancer vaccine based on mRNA tech was shown to be safe and capable of triggering an immune response in a small trial.
The Biden administration is preparing for legal psychedelics within two years
The Biden administration’s Department of Health and Human Services has sent a memo supportive of psychedelic therapies. What does that mean for the field?
“Jumping genes”: A new model of Alzheimer’s
A new hypothesis suggests that Alzheimer's disease is the result of "jumping genes" in the brain, not inflammation or plaque.
90% of drugs fail clinical trials – here’s one way researchers can select better drug candidates
It’s disappointing when the years of effort and resources spent to push a drug candidate to patients so often lead to failure.
As Ebola reaches Ugandan capital, vaccines race to catch up
Caused by the Sudan strain of Ebola, current vaccines and therapies approved for Ebola won’t work in Uganda. But these might.
Computer-designed miniproteins unleash a whole new kind of drugs
Using a computer program, researchers have created miniproteins that they hope can lead to new drugs.
San Francisco decriminalizes plant-based psychedelics
San Francisco joins Oakland, Santa Cruz, DC, and Denver in decriminalizing some psychedelics.
The first FDA-approved clinical trial of psilocin has begun
“This has never been done before,” says Filament’s CEO.
New drug combo is “a paradigm shift” in preventing asthma attacks
The combination of a rescue medication and a corticosteroid, taken as needed, reduced both short and long-term risk of asthma attacks.
New brain cancer treatment trialed in children for the first time
MRI-guided focused ultrasound has been used to deliver chemo into the brain of a pediatric cancer patient for the first time.
How cancer science is creating a sunscreen that lasts all day
NYU chemists have taken lessons learned from cancer drug development to create a longer-lasting sunscreen ingredient
Two African countries first to approve Oxford’s malaria vaccine, with 20 million doses on the way
Ghana and Nigeria have become the first two nations to approve Oxford’s vaccine against malaria.
Psychedelic research returns to Veterans Affairs
After decades, the Department of Veterans Affairs is once again investigating psychedelic therapies.
From drugs to chemical weapons with a flip of an AI switch
AI drug discovery models can be repurposed to darker ends — instead of discovering new treatments, they could create thousands of brand new chemical weapons.
Fiber is your body’s natural guide to weight management
Fiber is important not just for happy bowel movements, but also for your blood sugar, weight, and overall health.
Cancer is addicted to iron. It could be a fatal weakness.
By homing in on the high levels of iron in certain cancer cells, researchers have created a more targeted anticancer drug.
New mRNA therapy could bring an end to peanut allergies
A new peanut allergy treatment based on mRNA could potentially lead to therapies that prevent all types of allergies in people.
Cheap blood pressure med could help treat alcoholism
Spironolactone, a cheap medication used to treat high blood pressure, might also be able to help people overcome alcohol use disorder.
Breakthrough drug could save hundreds of thousands of children’s lives
A booster dose of the University of Oxford’s malaria vaccine demonstrated up to 80% efficacy in children over a year of follow-up.
How to use the brain’s own immune cells to stave off Alzheimer’s
Research suggests that microglia play a key role in preventing neurodegenerative diseases by helping to remove toxic waste.
Safer painkillers: A novel drug treats pain without killing people
Painkillers have nasty side effects, such as organ damage or addiction. Researchers have discovered a new drug that may cause none of these.
LSD effective as major depression therapy in phase 2 trial
MindMed and University Hospital Basel have announced top line results for their phase 2 trial.
Drug to treat alcoholism could also safely reduce anxiety
The alcoholism treatment disulfiram may be able to serve double-duty as an anti-anxiety medication, according to mouse studies.
Engineered bacteria may one day prevent kidney stones
In a small proof-of-concept study, an engineered E. coli was able to reduce levels of a kidney stone-causing chemical.
Tiny nanoscale drills can bore holes right through bacteria
Rice University researchers have developed tiny, bacteria-boring drills in an effort to stop superbugs.
First personalized CRISPR therapy approved for trial
The FDA has approved a trial for the first personalized CRISPR therapy, which was developed to treat Duchenne muscular dystrophy.
Reversing hearing loss with regenerative therapy
MIT spinout Frequency Therapeutics’ drug candidate stimulates the growth of hair cells in the inner ear.
A shapeshifting volcano virus’s secret has been discovered
The secret to a shapeshifting volcano virus may help us create new, better drug and vaccine delivery platforms.
New clinical trial is testing a ketamine skin cream for PTSD
A topical ketamine treatment designed to alleviate the symptoms of PTSD without causing hallucinations has entered clinical trials.
Nonprofit drugmaker Civica Rx is taking aim at the high insulin price
People living with insulin-dependent diabetes have been waiting a long time for it to be more affordable. Could things change?
“Stealth bomb” for cancer unlocks powerful immune attack
A "masked" cancer drug stealthily trains immune system to kill tumors while sparing healthy tissues, reducing treatment side effects.
$3.5 million treatment for hemophilia wins FDA approval
The FDA has approved biotech company CSL Behring's Hemgenix, a hemophilia B treatment that costs $3.5 million per dose.
Psychedelics open a new window on the mechanisms of perception
Some neuroscientists think psychedelics and the hallucinations they induce could help reveal how we generate our perceptions of the world.
Psychedelics are helping dying patients overcome their existential distress
End of life patients face existential and spiritual challenges other patients do not. Psychedelics may be uniquely suited to helping them.
FDA approves first-of-its-kind blood cancer treatment
The FDA has approved Johnson & Johnson’s Tecvayli, a new blood cancer treatment for people with relapsed or refractory multiple myeloma.
How the antidepressant Prozac could treat blindness
Prozac is a widely used antidepressant. Data indicates that the drug could be used to prevent blindness due to macular degeneration.
Chickenpox and shingles virus lying dormant in your neurons can reactivate and increase your risk of stroke
People with shingles have an approximately 80% higher risk of stroke than those without the disease, and researchers want to know why.
CRISPR eliminated heart damage in mice after a heart attack
A new CRISPR base editing therapy was able to prevent mice from suffering seemingly any heart damage following an induced heart attack.
Arkansas man receives world’s first eye transplant
The world’s first whole eye transplant puts doctors a major step closer to restoring vision with donor eyes in the future.
One shot of this COVID-19 drug reduces risk of death by 60%
In-development COVID-19 drug Peginterferon Lambda reduced risk of hospitalization or lengthy emergency room visits by 50% in a phase 3 trial.
Exercise boosts the brain — and mental health
New research is revealing how physical activity can reduce and even ward off depression, anxiety and other psychological ailments.
New study shows how electricity can turn on genes
A prototype wearable demonstrates a novel way to trigger gene expression: by zapping cells with electricity.
Herpes virus helped kill a deadly form of breast cancer in a clinical trial
A combination of an engineered herpes virus and chemo showed promise for treating triple-negative breast cancer in a small study.
A modified herpes virus completely wiped out a terminal cancer
In a small phase 1 trial of a herpes-based cancer therapy, one patient had their tumors completely eliminated.
Baby thrives after first-of-its-kind heart transplant
A baby’s first-of-its-kind heart transplant could help future patients avoid organ rejection and reduce the need for immunosuppressant drugs.
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Catalysts
This restaurant only hires recovering drug users
In partnership with Stand Together
After addiction killed 13 of their employees, this restaurant devoted itself to helping people in recovery.
Gain-of-function research is more than just tweaking risky viruses
Gain-of-function experiments in the lab can help researchers get ahead of viruses naturally gaining the ability to infect people in the wild.
Potential way to treat anorexia found in microbiome
New research links the gut microbiome, an ecosystem of viruses, bacteria, and fungi, to the development of anorexia nervosa.
Mark Cuban launches online pharmacy to cut drug prices
Billionaire investor Mark Cuban has launched an online pharmacy designed to cut the cost of generic drugs by as much as 99%.
Engineered bacteria may fight this brain-damaging genetic disorder
A possible phenylketonuria therapy using engineered bacteria has shown positive results in a small phase 2 trial.
The source of a strange anti-cancer compound is found in Florida
Researchers have discovered that common soft corals are the source of a sought-after anti-cancer compound.
Psychedelics, brain implants, and the future of chronic pain relief
The future of chronic pain relief could include psychedelics, gene therapies, brain implants, and other cutting-edge alternatives to opioids.
Drug that cleans up cholesterol may reduce post stroke dementia
Researchers look to an FDA-approved drug ingredient that can "scoop-up" and store cholesterol and possibly stave off post stroke dementia.
The groundbreaking plan to map the entire human immune system
Powered by AI and a vast trove of data, the Human Immunome Project aims to fully map the most complex system in the human body.
DMT therapy appears effective for depression in phase 2 clinical trial
London-based Small Pharma has released positive top-line results for their phase 2a trial of DMT as an antidepressant.
New tiny home village for unhoused people to open in 2023
Salt Lake City is building a new tiny home village to help Utahns experiencing chronic homelessness get off the street permanently.
America’s “Test to Treat” has failed. Here’s how to fix it.
So far, Test to Treat has largely failed to get antivirals for COVID-19 to patients that need them — but the initiative can still be fixed.
Scientists discover possible precursor to a Parkinson’s drug
Scientists have optimized a peptide known to prevent the “protein misfolding,” that causes Parkinson’s disease. This could be a precourser to a disease treatment.
The science of habits
Whether you’re trying to break a bad habit or start a good one, psychologists have some tips to get you started.
How we treat inflammation may be causing chronic pain
Reversing common belief, researchers at McGill say treating inflammation may be causing chronic pain, not preventing it.
Yale study of DMT for depression is encouraging
Yale researchers have conducted a small study finding DMT is safe and tolerable enough for more research.
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Challengers
At-home ketamine therapy — are you ready?
Will this at home “tripping kit” change mental health forever?
5 biotech trends to watch in 2023
After a monumental year of breakthroughs, scientists, investors, and CEOs share which areas of biotech they are eagerly watching this year.
New children’s malaria treatment clears out infection in liver
Malaria can hide in the liver, causing relapse months or years later. Now, public health officials have a new treatment to prevent relapse for children under 16.
AI maps psychedelic “trip” experiences to regions of the brain – opening new route to psychiatric treatments
To better understand how these effects manifest in the brain, we analyzed over 6,000 written testimonials of hallucinogenic experiences.
Pfizer’s nasal spray for migraines is heading to pharmacies
The FDA has approved Pfizer’s zavegepant, a nasal spray for migraines that can ease pain in as few as 15 minutes.
Theory of mind: What chess and drug dealers can teach you about manipulation
Every social interaction is a game of chess, trying to get inside someone’s head to navigate what they are thinking or what they will do.
How three kids got kidney transplants without immunosuppressants
Stanford researchers have developed a new technique that allowed three children to receive kidney transplants without immunosuppressants.
Man receives donor lung through tiny 3-inch incision
The first fully robotic lung transplant was completed in Spain by surgeons using a robot and a brand-new access point.
Harm reduction vending machines are coming to New York
New York City has announced a pilot program installing public health vending machines with overdose drugs and clean needles.
Scientists uncover key to future hepatitis C vaccine
While treatments are available for HCV-related infections, they are expensive, hard to access, and do not protect against reinfection.
A malaria-fighting antibody has passed phase 2 trials
An antibody designed to prevent malaria infection has proven effective in phase 2 trials in Mali.
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Heretics
Should extreme biohacking be a human right?
“I want to genetically modify humans. I want to create a coronavirus vaccine in my kitchen. Because I can. Because it’s beautiful and cool. But like, you can’t say that shit.”
Canadian students discover EpiPens will turn toxic in space
Canadian students launched EpiPen solution into suborbital space, and what came back was no longer life-saving medicine.
Canada approves psychedelic therapy
A new amendment approving psychedelic-assisted therapies on a case-by-case basis has taken effect.
AI dramatically improved mRNA vaccines in just 11 minutes
A new AI tool can find the most stable mRNA sequence for a vaccine, leading to more effective shots that are less prone to degradation.
DeepMind’s AI lights path to faster drug development
Alphabet has announced the launch of Isomorphic Labs, an AI-driven drug discovery company built on research from its DeepMind subsidiary.
Mindfulness can slow down the brain’s aging and more
The benefits of practicing mindfulness carry over into everyday life – even when you aren’t actively meditating.
Traditional Thai cannabis cooking is back on the menu
Cannabis cooking has long simmered in Thailand. With the ruling junta’s new drug policies, the traditional dish is now making its way onto restaurant plates.
Rhode Island will be the first state to open safe drug consumption sites
In an important test of drug harm reduction techniques, Rhode Island is set to become the first state to open safe consumption sites.
Genes from over 5,000 stroke patients hint at surprising treatment
A study of nearly 6,000 stroke patient genomes suggests a treatment idea abandoned for decades should get a second look.
Nanobots are real, and they can battle bacteria
Researchers have developed antibiotic nanobots that can traverse a wound on their own.
CRISPR tool slashes bad cholesterol by 56% in monkeys
Tune Therapeutics has successfully lowered the cholesterol levels of monkeys using a version of CRISPR that doesn’t permanently alter DNA.
Scientists use CRISPR to add an alligator gene into catfish
By using CRISPR to insert an alligator gene into catfish, Alabama scientists radically increased their disease resistance.
It’s time to change how we think about electroshock therapy
Electroconvulsive therapy is more effective than ketamine at treating severe depression, according to a new meta-analysis.