Showing 678 results
ADHD drugs could alleviate symptoms of Alzheimer’s
Scientists reviewed 40 years of clinical studies that assessed the effects of NA-targeting drugs, such as certain ADHD drugs, on Alzheimer’s.
AI-developed drug for deadly lung disease reaches phase 2 trials
AI-driven drug development has led to the launch of phase 2 trials of a drug to treat idiopathic pulmonary fibrosis (IPF).
Radioactive drugs are transforming cancer treatment
Radiopharmaceuticals allow doctors to directly target patients' cancer cells and avoid healthy tissue typically damaged by radiation therapy.
Weight-loss drug cut the risk of heart attack and stroke by 20% in large trial
The weight-loss drug semaglutide reduced patients’ risk of heart attacks, strokes, or death from heart disease by 20% in a large trial.
Lung cancer drug slashes patients’ risk of death by 51%
Osimertinib, an FDA-approved lung cancer drug, slashes the risk of death for certain patients by 51%, according to new trial results.
New Alzheimer’s drug slows cognitive decline by 35%
Eli Lilly’s new Alzheimer’s drug, donanemab, slowed cognitive decline by 35% in a phase 3 trial, but two people died from side effects.
New drug for fatty liver disease cuts fat by 65%
A new NASH treatment, efruxifermin, significantly reduced liver fat when combined with a GLP-1 drug in a small trial.
Drug to grow new teeth heads to human trials
A drug that causes animals to grow new teeth could one day allow us to regenerate teeth lost to injury, disease, or old age.
AI-discovered drug for ALS enters human trials in just four years
Verge Genomics has begun a trial of their AI-found ALS drug candidate, one of the first tests for this new method of drug discovery.
Cheap drug appears to cut long COVID risk by 41% in small study
The diabetes drug metformin cut COVID-19 patients’ risk of later developing long COVID by 41% in a small study.
A simple tweak could improve treatment of a deadly herpes brain infection
Anti-inflammatory drugs could potentially prevent herpes encephalitis from causing permanent brain damage.
Pill version of obesity drug reduced weight almost 13% in new trial
Novo Nordisk has announced positive results for an oral version of the popular weight loss drug sold as Ozempic and Wegovy.
Existing heart drug may boost treatment for skin cancer
The FDA-approved heart medication ranolazine boosted the efficacy of a BRAF inhibitor in mouse models of melanoma, the deadliest skin cancer.
New drug delivery tech could ensure you never forget your meds
Rice University's new drug delivery tech uses biodegradable microparticles to administer medications exactly when and where they are needed.
Cancer med appears to prevent brain aneurysms
Japanese researchers have discovered that the cancer drug sunitinib can prevent the formation of brain aneurysms in mice.
Psychedelic inspires discovery of two new drug candidates for depression
Researchers have found ibogaine-inspired compounds effective in treating depression and addiction in mouse models.
This “bridge” between chemo and cancer solves a big problem for treatment
To improve leukemia treatment, Australian researchers have created a bispecific antibody that connects chemo drugs to cancer cells.
New obesity drug cut weight by 58 pounds in trial, making it the most effective yet
Eli Lilly announced results from a phase 2 clinical trial of the newest entrant in the obesity treatment space.
Alzheimer’s disease: an illness that needs a long overdue cocktail
Scientists are starting to agree that the "holy grail" solution for Alzheimer's is more likely to be a drug cocktail than a single treatment.
Cancer treatment is about to get a reboot, thanks to AI
Techniques borrowed from astrophysics are helping to advance personalized cancer treatments beyond what genetics can tell us.
Spread of deadly cancer delayed by organ transplant drug
A groundbreaking discovery on how pancreatic cancer spreads could lead to better therapies for the hard-to-treat disease.
SpaceX successfully launches world’s first “space factory”
SpaceX has successfully deployed a “space factory” developed by startup Varda Space Industries to manufacture drugs in microgravity.
Rapamycin: The unlucky history of the most powerful anti-aging drug
When rapamycin research was revived, it was found to have both anti-cancer and anti-aging properties. Here's what researchers say today.
New drug could extend lives of people with deadly bone cancer
A new drug might extend the lives of people with bone cancer without subjecting them to painful or unpleasant treatments.
The AI healthcare revolution has begun
The ability of AI to diagnose diseases, discover drugs, and even perform surgery is increasing rapidly — but will patients accept Dr. AI?
“Brain-eating” amoeba beaten by old European drug
A man infected by a deadly brain-eating amoeba is on the road to recovery thanks to a decades-old drug used to treat urinary tract infections.
ADHD drugs might also treat Alzheimer’s disease
Scientists reviewed 40 years of clinical studies that assessed the effects of NA-targeting drugs, such as certain ADHD drugs, on Alzheimer’s.
Ultrasound could help us fight the deadliest cancer
In a small study, Northwestern researchers were able to get chemo drugs into the brains of glioblastoma patients with implanted ultrasound devices.
Study finds tracking brain waves could reduce post-op complications
Researchers found brain wave signatures that could help determine when patients are transitioning into a deep state of unconsciousness.
New drug candidates found in an unlikely place
Costa Rica’s famed sloths harbor bacteria in their fur which can create antibiotic compounds — a potential source of future therapies.
Cheap liver drug can prevent COVID-19
A cheap, readily available drug used to treat liver disease could also prevent COVID-19 infections — regardless of the variant.
“Nature’s own Ozempic” or berberine is all over social media
Does berberine work as well as Ozempic to help people lose weight? Social media seems to think so, but it's not likely.
Something found in bats could help us survive infections and inflammation
This protein may help bats survive viral infections and could be the springboard for new anti-inflammatory drugs.
New biomarker test accurately predicts who will respond to antidepressant
Alto Neuroscience’s depression drug seems effective in early trials, a proof-of-concept for biomarker-based design.
Hollow “seed” shrinks cancerous tumors from the inside
A new drug delivery system for pancreatic tumors could dramatically decrease medication dosages, helping minimize unpleasant side effects.
Tirzepatide: A novel obesity drug ushers in a new era of weight loss — because this one works
Patients who received tirzepatide in a recent clinical study lost more than 20% of their body weight (52 pounds, or 23.6 kg).
New nasal spray aimed at reversing fentanyl overdoses is now approved
A new overdose-reversing spray that works fast but lasts longer has been approved by the FDA, and will be available by the fall at earliest.
Narcan is now available over-the-counter in the US
Naloxone administered by nasal spray can be a lifesaving drug with minimal side effects. It's now approved for over-the-counter use in the U.S.
Old herpes drug helps kill deadly superbug
The anti-herpes drug edoxudine can weaken the deadly superbug K-pneumoniae, potentially offering a new weapon against antibiotic resistance.
Breakthrough drug cures sleeping sickness with one dose
A new, one-dose treatment for lethal sleeping sickness was 95% effective at clearing the parasite from patients.
First ever therapy for rare genetic disorder now approved
The FDA has approved the first drug for Rett syndrome, a genetic neurodevelopmental disorder, which disproportionately affects women and girls.
Viruses cause 200+ diseases. This one drug may be able to treat them all.
New Zealand-based startup Kimer Med wants to create an antiviral that would be effective against many known viruses — and unknown.
New kind of pill cut “bad” cholesterol up to 60% in clinical trial
In a phase 2 trial, a daily oral medication reduced LDL cholesterol levels by up to 60%.
Breakthrough study discovers that psychedelics breach our neurons
Researchers have discovered that psychedelics can activate 5-HT2A receptors inside of cortical neurons, a possible cause of their therapeutic effects.
New fentanyl vaccine could help avoid relapses and overdoses
An in-development fentanyl vaccine that prevents the drug from entering the brain could one day help people avoid relapsing or overdosing.
DMT appears effective for depression up to six months later
Small Pharma has announced the results of a six-month follow-up for their phase 2a trial of DMT for depression.
Study suggests that exercise should be prescribed to mental health patients
Researchers concluded that exercise should be prescribed to patients with mental health issues before psychiatric drugs.
Old Parkinson’s drug helps teens with type 1 diabetes
The Parkinson’s disease drug bromocriptine lowered blood pressure and reduced aortic stiffness in young people with type 1 diabetes.
Ancient viruses in the human genome can help fight cancer
Armed with a DoD grant, researchers are harnessing the genetic code of ancient viral infections to fight prostate cancer.
Ketamine is as effective as ECT for depression, study shows
A trial of patients with treatment-resistant depression found ketamine to be at least as effective as electroconvulsive therapy.
One shot could stop severe bleeding and save thousands of lives
A potentially lifesaving treatment to stop severe postpartum hemorrhage could soon be more accessible to the people who need it the most.
A single dose of an old drug could save 2 million mothers from sepsis every year
A large international study has found that a single oral dose of a common antibiotic can “significantly” reduce the risk of maternal sepsis
Does online opioid treatment work?
A sudden shift to virtual health care has increased access — and possibly outcomes — for patients with opioid use disorder.
Lab-grown meat techniques aren’t new
Cell cultures are common tools in science, but bringing them up to scale to meet society’s demand for meat will require further development.
New chemo pump for brain tumors could avoid side effects
A fully implantable chemo pump could help extend the lives of people with deadly brain tumors while minimizing treatment side effects.
Insulin grown in lettuce can be taken orally
New synthetic insulin harvested from lettuce plants can be made cheaply, taken orally, and transported at room temperature.
Probiotic gut bacteria can produce a vital Parkinson’s drug
L-DOPA is a miraculous Parkinson’s drug with terrible side effects. Researchers have created drug-producing bacteria that may help.
5 drugs that changed the world (and what went wrong)
Anesthesia, penicillin, antibiotics, diazepam, and the birth control pill have all radically changed our lives.
FDA approves new Alzheimer’s medication
Lecanemab, a new Alzheimer’s medication shown to slow cognitive decline in patients, has been granted accelerated approval by the FDA.
HIV drug could improve memory
The common HIV drug maraviroc improved memory linking in aging mice and might be able to help people experiencing memory loss, too.
New study will put the leading theory about Alzheimer’s to the test
Washington University in St. Louis is embarking on a drug trial that may also put the amyloid hypothesis to its ultimate test.
An old anti-psychotic offers a new way to treat chronic pain
Researchers have found that an old anti-psychotic drug may have implications for chronic pain and cancer.
One shot epilepsy treatment reduced seizures by 95% in first two patients
A stem cell-based treatment for epilepsy slashed the number of seizures experienced by two trial participants by 95%.
A new drug could repair stroke damage to memory and movement
A new drug can repair stroke damage in mice, improving memory and motor skills. If it works in humans, it could lead to a paradigm shift in stroke treatment.
Meth addiction treatments are finally on the horizon
New antibody and drug therapies may soon help treat meth patients, who currently have no pharmacological interventions.
New Alzheimer’s drug slows mental decline by 27% in clinical trial
Eisai and Biogen are reporting that their new Alzheimer’s antibody slowed cognitive decline by 27% in a global trial.
Scientists make pain relievers like Tylenol from pine trees rather than fossil fuels
Chemists have shown how to manufacture ibuprofen and acetaminophen using a waste product from the forestry and paper industries.
A new class of antidepressant works in 2 hours
Most types of antidepressants work by increasing neurotransmitter levels throughout the brain, which take weeks. A new drug takes hours.
A new delivery method for drugs that can’t withstand stomach acid
In order for a drug to get to the small intestine, it must first get past the highly acidic environment of the stomach.
Archaeologists identify contents of ancient Mayan drug containers
Archaeologists used new methods to identify contents of Mayan drug containers, discovering a non-tobacco plant.
“DALL-E 2 of biology” designs proteins for new drugs
The Chroma AI's ability to design proteins with structures no one has ever seen before could revolutionize medicine.
An old HIV drug may treat Down syndrome
A common HIV drug could potentially be a Down syndrome treatment, improving cognition in mouse models of the condition.
New evidence that teeth can fill their own cavities
Researchers find that, in some cases, tooth dentin can be regrown instead of needing to be replaced with man-made composite.
Biden pardons federal cannabis possession cases, urges states to do the same
The Biden administration is pardoning federal possession offenses, encouraging states to do the same, and reexamining its drug scheduling.
LSD flashbacks and a psychedelic disorder that can last forever
LSD flashbacks have been studied for decades, though scientists still aren't quite sure why some people experience them.
Study finds mindfulness as effective as medication for anxiety
An intensive form of mindfulness was found as effective as Lexapro in treating anxiety in adults in the first head-to-head comparative study.
New kind of schizophrenia drug aces human trial
KarXT, a new schizophrenia treatment that addresses a wider range of symptoms than existing meds, has aced a phase 3 trial.
A functional cure for brittle diabetes is now available in the US
Islet transplantation, a procedure shown to functionally cure some people with hard-to-control brittle diabetes, has been approved in the US.
Do we finally know what causes Alzheimer’s?
The first treatments proven to slow cognitive decline in Alzheimer’s are helping settle a decades-long debate about how the disease starts.
Targeted therapy kills every type of cancer in the lab
City of Hope researchers are trialing a targeted therapy shown to kill more than 70 types of cancer in preclinical tests.
Two FDA-approved drugs may improve Alzheimer’s symptoms
A retrospective study found that Alzheimer’s symptoms improved in patients who took two FDA-approved drugs that treat psychiatric disorders.
Experiment regenerates a damaged kidney for the first time ever
A new treatment that caused the diseased kidneys of mice to regenerate might one day do the same for people.
New exercise study could find drugs that mimic working out
MIT and Harvard researchers mapped out many of the cells, genes, and cellular pathways that are modified by exercise or high-fat diet.
Scientists discover “anxiety gene” in the brain — and a natural way to turn it off
The discovery of an "anxiety gene" — and a natural way to put the brakes on it — in mice could lead to new treatments for anxiety disorders.
Organ regeneration could overcome liver failure, without a transplant
Patients wait from 30 days to over five years to receive a liver transplant in the U.S. What if the liver could regenerate itself instead?
Opioid overdose: A bioethicist explains why restricting supply may not be the right solution
Since the unpredictability of drug supply increases overdose risk, making the drug supply predictable should be part of the solution, right?
New “future-proof” drug can fight COVID-19 and the common cold
Researchers have identified a compound capable of stopping multiple coronaviruses in cell and tissue models.
Withdrawal symptoms from antidepressants can last over a year
A scientific review found that withdrawal symptoms from antidepressants and antipsychotics can last for over a year.
Scientists claim “never before” seen results in ALS clinical trial
The ability of tofersen, a gene-based treatment for ALS, to improve symptoms is being hailed as a “treatment milestone.”
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Heretics
“I work on dog lifespan extension”
Are you ready for drugs that make you live longer?
Have scientists found a “brake pedal” for aging?
A new protein discovery may have highlighted a "switch" in brain cells that slows down inflammation and aging.
New RSV shot protects babies against dangerous lung infections
The FDA has approved nirsevimab, an RSV shot that protects babies against the leading cause of infant hospitalizations in the US.
Tiny robots completely clear out deadly pneumonia infection in mice
Researchers have created microscopic robots capable of clearing pneumonia from the lungs of mice.
Your genes may impact psychedelic experiences
UNC researchers have found evidence that the genetic makeup of a crucial receptor may impact your psychedelic experience.
Epilepsy surgery has a success rate of only 50%. This digital brain may change that.
Using patient data and AI, French researchers have created a digital model of the brain to figure out which brain region needs removed.
Male birth control options are in development, but a number of barriers still stand in the way
A survey of over 9,000 men in nine countries found that over 55% would be willing to use a new method of male birth control.
The imagination effect: A history of placebo power
The famous placebo effect has a long, rich history — it certainly had an outsized role in the medicine of centuries past.
Got COVID but felt fine? It may be your genes.
A person’s chances of having asymptomatic COVID are dramatically increased if they possess a certain genetic mutation.