Showing 678 results
New approach for mRNA HIV vaccine passes first human trial
There is currently no HIV vaccine, but a new technique which produced specific immunity cells in humans may pave the way to one.
Harvard has a vaccine against septic shock
A new vaccine platform based on biomaterial may eventually provide rapid protection against multiple bacterial threats.
Inhaled coronavirus drug shows promise in small trial
An inhaled coronavirus drug containing interferon beta decreased patients’ chances of becoming severely ill by 79%, according to its creator.
Oxford malaria vaccine is 77% effective in young children
A malaria vaccine developed by Oxford University was 77% effective at protecting children during a phase 2 trial in Africa.
How you breathe affects your brain
A psychiatrist and neuroscientists investigate how breathing affect the brain and biological markers of stress and immune function.
“Antibody inhaler” could rapidly treat—and prevent—COVID-19
Scientists have discovered a new antibody therapy that can be inhaled to provide treatment and temporary immunity to the coronavirus.
4 people in the world have a mysterious dementia. Could it hold a key to Alzheimer’s?
Alzheimer’s has proved difficult to treat. But solving the mystery of this ultra-rare frontotemporal dementia may unlock new understanding.
Phage therapy kills superbug behind many ICU infections
Combining a bacteria-killing virus and an antibiotic was able to wipe out an infection of the superbug A. baumannii in mice.
An IBM quantum computer is being built at a US hospital
An IBM quantum computer is being installed at the Cleveland Clinic as part of the organizations' Discovery Accelerator collaboration.
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Make It Count
Building homes with hemp
In partnership with Million Stories
Cannabis was an ancient building material. Now it’s legal again - and coming to a home near you.
Old dogs are helping scientists combat human aging
By studying donated tissues stored in a pet dog biobank, researchers have uncovered a genetic link between brain aging in canines and humans.
We’re one step closer to a malaria-free world
Now that malaria has been eliminated in China, the long-held dream of a malaria-free world is one nation closer to reality.
Here’s why sensory perception research was awarded a Nobel Prize
Physiologists David Julius and Ardem Patapoutian were awarded the Nobel Prize in Medicine for their research on human sensory perception.
Antidote saved 100% of bees from lethal pesticide
Beehives are under threat from common insecticides. But researchers created pollen-like microparticles to deliver an antidote.
Redesigned syringe could increase global access to medicine
A double-barrel syringe developed at MIT makes it possible to inject highly viscous biologics, making them more accessible to patients.
Bacteria nanomachines fire smart missiles that could replace antibiotics
Researchers want to use bacteria-made nanomachines called tailocins to help fight enemy bacteria strains in the human body.
New ALS treatment appears to slow disease progression
A new ALS treatment that appears to slow disease progression offers hope to those battling the incurable neurological disorder.
Mount Sinai is opening a psychedelic research center
A pacesetting institution, the Icahn School of Medicine at Mount Sinai is opening a psychedelic research center focusing on MDMA and trauma.
Reasons to be optimistic in 2022
It can be tough to feel positive after the past two years. But a closer look at the recent past provides reasons for optimism in 2022 and beyond.
Psilocybin therapy appears to dramatically reduce depression
Psilocybin therapy — a combination of traditional therapy and supervised “trips” on the magic mushroom compound — shows promise as a depression treatment.
“Candy flipping” — mixing MDMA and LSD — is hitting the lab
A clinical trial of mixing LSD and MDMA, known as “candy flipping,” wants to see if molly can take a trip’s edge off and make LSD therapy more effective.
Human-like "organ chips" could eliminate animal studies
To rapidly test for COVID-19 treatments without animal studies, researchers make a model human body out of “organ chips.”
CBD does not impair driving, study finds
A new study has demonstrated that CBD is safe for driving, while the effects of THC last only a few hours. This work could inform cannabis use laws.
Designer antibodies could help treat and prevent COVID-19
A pair of new trials will test the ability of designer antibodies to not only treat COVID-19, but also potentially prevent coronavirus infections.
3D-printed nose cartilage may someday fix your face
Researchers have developed a way to bioprint nose cartilage that they hope will one day minimize the need for invasive harvesting from the ribs.
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Dope Science
Are social media giants censoring life saving drug research?
The first casualty of war is truth, and that applies to the war on drugs. Some are fighting back with harm reduction and drug education, yet they’re facing opposition from an unexpected source.
Researchers create blueprint for the “love hormone” receptor
The shape of the love hormone receptor is finally revealed in a 3D map created by researchers at the University of Zurich.
Study: Risk of death from COVID-19 is 45% lower on arthritis drug
The arthritis drug tocilizumab may lower ventilated patients' risk of death from COVID-19 by 45%, according to a retrospective study.
The first life-saving coronavirus drug is a common steroid
A large clinical trial in the U.K. identified the cheap, widely available steroid dexamethasone as potentially the first life-saving coronavirus drug.
Coronavirus treatment update: Where we stand today
Our latest coronavirus treatment update highlights the options that appear to work, ones that might, and ones that failed to live up to their promise.
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Catalysts
Hacking the child brain: The 5 step process to unlock every kid’s potential
In partnership with Stand Together
The biggest myth in education is that some kids are destined for greatness and others aren’t.
How to mass produce your own organs
Bioprinting could be the next frontier of personalized medicine.
This startup is creating a toothpaste for your peanut allergy
Immunotherapy for allergies can help reduce allergic reactions, but it needs to be daily. Could toothpaste provide a solution?
Brain-wide gene editing may one day treat Alzheimer’s
Researchers have developed a brain-wide gene editing technique that treated Alzheimer’s disease in mice.
What it’s like to do a human challenge trial
Human challenge trials are risky, but they could help us avoid another prolonged pandemic.
First coronavirus antibody drug trial launches in us
An antibody drug developed to treat people with COVID-19 — and potentially prevent new infections — is now being tested in humans.
NYU is launching a center for psychedelic medicine
NYU’s Center for Psychedelic Medicine will serve as the nexus for the school’s psychedelic research, as well as provide training to budding researchers.
Blood test for Alzheimer’s now available at doctors’ offices
For the first time, a blood test for Alzheimer’s disease has received approval to be used in doctors’ offices in the U.S.
Penn scientists correct genetic blindness with a single injection into the eye
Antisense oligonucleotide therapy uses small molecules to alter RNA. Researchers have now used those molecules to alleviate a genetic form of blindness.
Customized stem cells could show us how dementia happens
By turning human cells into induced pluripotent stem cells, researchers hope to finally map the genetic path to Alzheimer’s disease.
The case for love-enhancing drugs
Drugs don’t just affect the user; they shape relationships too. And a pair of bioethicists thinks we should consider them for relationship enhancement.
Microdosing LSD may provide pain relief
Since the 1960s, LSD has been seen as a potential painkiller. Now, new research suggests microdosing LSD may indeed provide relief.
App brings psychedelic-assisted therapy into your home
The Field Trip app aims to help people get some of the benefits of psychedelic-assisted therapy outside the confines of a clinic.
How to stop COVID-19's killer cytokine storm
COVID-19 can cause a potentially lethal cytokine storm, a runaway immune system response. Researchers are studying drugs they hope can calm the storm.
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Just Might Work
Can we hack sugar to be healthy?
Is there such a thing as healthy sugar? Food scientists in Israel are hacking the sugar molecule itself – eliminating the need for subpar alternatives.
New drug could provide long-term HIV prevention
HIV prevention typically requires a daily pill. A new, injectable drug may be able to work for over a month at a time.
CRISPR fixes rare mutation for the first time in a live animal
For the first time in a live animal, researchers have successfully reversed a gene mutation, called a “duplication mutation,” by gene editing.
Designer DNA hunts down multiple myeloma in mice
Researchers have developed designer DNA that kills cancer stem cells at their roots, showing early signs of success preventing relapse in mice.
Your incentives to get the COVID-19 vaccine
If protection against a potentially deadly virus isn’t enough, there are these added incentives to get the COVID-19 vaccine.
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Dope Science
The Drug Users Bible: A guide to safe drug use
Over a 10 year period, Dominic Milton Trott self-administered 157 psychoactive drugs and documented his experiences on each one. He then created the book, The Drug Users Bible, to inform curious minds about safe drug use.
Can a dog vaccine for Valley fever lead to a human one?
Cases of Valley fever, a fungal infection, have risen dramatically over the decade. Researchers hope a dog vaccine may lead to one for humans.
We need to know about progress if we’re concerned about the world’s large problems
Our World in Data explains their mission to publish the “research and data to make progress against the world’s largest problems.”
Cone snail venom may help treat malaria
Clumps of infected red blood cells can make malaria dangerous even after its parasite is treated. Cone snail venom may one day help.
Scientists want to study your at-home psychedelic mushroom experiences
Scientists are looking for people planning to trip on psychedelic mushrooms for a new study focused on people’s “real-world” experiences with psilocybin.
Psychedelic toad venom explained
5-MeO-DMT, a psychedelic found in toad venom, causes mushroom-intense trips that are over quick. Could it have more accessible therapeutic potential?
Immune signals may predict severe cases of COVID-19
Severe cases of COVID-19 involve a runaway immune response called a cytokine storm. Immune system “signatures” may sharpen doctor’s forecasts.
New brain implant can be charged wirelessly
A new brain implant contains wireless charging tech that could eliminate the need for surgeries to remove and replace drained batteries.
Researchers have built a mini-lab for mini-brains
Researchers have created a “tiny machine” to better study brain organoids, clumps of stem cells that simulate the brain.
Ketamine discovery may lead to new antidepressants
Researchers have uncovered new insights into how ketamine affects the brain, potentially illuminating the path to new antidepressants.
Genetically modified pigs get green light from FDA
The FDA has approved Revivicor’s genetically engineered GalSafe pigs for use as food or medical products — a first for genetically modified animals.
“Antivitamins” could be the cure for antibiotic resistance
The B1 antivitamin helps bacteria kill competing bacteria, leading researchers to suspect it could help us fight antibiotic resistance and superbugs.
Flu drug may be an effective new coronavirus treatment
The Japanese flu drug favipiravir is an effective and safe new coronavirus treatment, Chinese officials claim after testing it on 340 patients.
HIV can hide inside human cells for years. Can CRISPR cut it out?
Using CRISPR to stop the replication of SIV, a primate virus closely related to HIV, researchers may have taken a step to wiping the virus out in the body.
Base editing could cure a host of genetic diseases
Base editing has proven useful for correcting disease-causing point mutations in animals — and now, human trials are on the horizon.
Friendly little mice are helping us understand the effects of LSD
Researchers at McGill have discovered the mechanisms behind the sociable effects of LSD in mice.
Can a lab-grown uterus treat infertility?
A bioengineered uterus could open up treatment options for women facing infertility.
Safe injection sites are legal, US court rules
A U.S. judge has ruled that safe injection sites, places where users can consume drugs under medical supervision, don’t violate federal drug laws.
“Google Maps for the human body” offers a deep view inside our trillions of cells
Researchers are creating an interactive, 3D map of the human body to help identify and prevent disease.
Ibogaine: The psychedelic cure?
Ibogaine, an African psychedelic drug which comes from the iboga plant, is used for both religious rites and drug addiction treatment.
It's now easier to see individual atoms, thanks to new tech
With improved tech, two teams have sharpened cryo-electron microscopy to be able to see individual atoms.
Antiviral pill shows promise as treatment for coronavirus
The oral antiviral drug EIDD-2801 has emerged as a promising treatment for coronavirus, performing well in the lab and in mouse studies.
An LSD trip “off-switch” may be coming soon
Pharmaceutical startup MindMed is developing tech it believes could serve as an “off switch” for an LSD trip during therapy sessions.
California city ends its chronic homelessness
Bakersfield, California, has effectively ended its chronic homelessness through an initiative focused on the collection of real-time data.
DeepMind AI cracks the code of protein structures
A protein’s structure is crucial to its function. Predicting how a protein will fold was a challenge decades in the making — and answered by DeepMind.
"Autoantibodies" may be causing COVID-19 blood clots
COVID-19 blood clots may be caused by autoantibodies, which attack the body’s own tissues and organs instead of intruders.
“Off-switch” in mouse brains offers new hope for pain relief
A newly discovered part of the mouse brain appears to naturally stop pain processing, and it could lead to more robust pain relief options in the future.
Personalized skin cancer vaccine is made from tumor cells
A personalized skin cancer vaccine developed from melanoma survivors’ own tumor cells has shown promise in a small trial.
Microdosing marijuana can relieve chronic pain
Microdosing marijuana can relieve chronic pain without impairing a person’s ability to think clearly, according to a new study.
Can RNA create a malaria vaccine?
An effective malaria vaccine could save hundreds of thousands of lives each year. Can RNA vaccines like the ones fighting SARs-CoV-2 tackle another disease?
FDA to begin testing chloroquine as coronavirus treatment
The FDA has announced plans to begin testing chloroquine, an anti-malaria drug, as a potential treatment for the novel coronavirus behind COVID-19.
MDMA therapy and the promise of psychedelics
Despite years of work with a "stellar" therapist, Charlotte needed more. She turned to MDMA therapy.
CRISPR used to edit HIV cure into monkey embryos
A mutation of the CCR5 gene can cure HIV — and thanks to CRISPR, scientists may soon be able to study it in animal models.
New vaginal ring reduces risk of HIV and pregnancy
A vaginal ring that serves double duty as both long-term contraception and convenient HIV prevention showed promise in a small study.
This company is using beer yeast to make psilocybin
Brewing the magic in Psilocybe cubensis is difficult at scale. One Danish company thinks beer yeast may be the answer.
Blood plasma from coronavirus survivors could save lives
A drug company is using the blood plasma of coronavirus survivors to develop a treatment for those still battling the disease.
Could VR change how you trip on ketamine?
Virtual reality meets ketamine therapy to help treat pain, anxiety, and depression, to name a few.
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Dope Science
I use ketamine for depression – here’s how it works
Commonly known as a party drug, ketamine’s powerful effects on the brain have led doctors to further explore its medical potential. Now, the animal anesthetic is providing relief and hope for people with severe depression.
New vanishing wound dressing heals skin with minimal scarring
A new kind of hydrogel dressing improves wound healing and minimizes scarring by kicking the adaptive immune system into gear.
CRISPR scientists win Nobel Prize in chemistry
For the first time, the Nobel Prize in chemistry has gone to two women: CRISPR scientists Emmanuelle Charpentier and Jennifer A. Doudna.
How we doubled our life expectancy in the last 100 years
“The idea of taking a pill and getting better is actually a very recent invention.”
A lesson on empathy from a people-first CEO
In partnership with Conscious Capitalism
In an increasingly competitive corporate world that so often prioritizes profits over people, one CEO is flipping the script and calling attention to the importance of empathy in the workplace.
Genetically engineering the first hypoallergenic cat
Scientists are attempting to create the world’s first truly hypoallergenic cat by deleting the feline gene that causes cat allergies.
Ketamine explained: Understanding the special k drug
Ketamine, known recreationally as the “Special K” drug, is a trance-inducing anesthetic that researchers believe has more powerful uses off the dance floor.
Can AI predict which depression treatment is most effective?
Artificial intelligence-powered algorithms that analyze brain scans are showing promise in helping doctors find an effective depression treatment on the first try.
Fireside Project is a support line for your bad trip
Fireside Project is a nonprofit that is providing a support line for your challenging psychedelic experiences — read: bad trip.
Cancer immunotherapy “baits” the immune system into attacking hidden lung tumors
When cancer spreads, it often ends up in the lungs. ImmunoBait can ride a red blood cell in mice to deliver cancer immunotherapy where they live.
Stopping nightmare disorder with a prescription-only watch
A prescription-only watch that treats nightmare disorder is the latest in a growing subset of health technologies called prescription digital therapeutics.
AI helps scientists discover powerful new antibiotic
Using a computer model powered by artificial intelligence, researchers at MIT have identified several promising candidates for powerful new antibiotics.
How organoids are helping scientists fight the coronavirus
Researchers are turning to organoids — lab-grown clumps of cells that mimic human organs — in an effort to better understand the coronavirus.
Immune proteins show promise as COVID-19 treatment
Immune proteins called interferons appear useful as a COVID-19 treatment if given to patients before an infection becomes severe.