Genetics
Ex-NASA engineer Mark Rober created the world’s smallest Nerf gun — from DNA
Mark Rober and Pallav Kosuri created a Nerf gun so tiny they had to build it out of DNA. This DNA "origami" has the potential to revolutionize engineering.
New CRISPR system is 66% smaller but just as powerful
A new CRISPR system is just as efficient as CRISPR-Cas9 but much smaller, which could make it easier to deploy in people.
Adding spider DNA to silkworms creates silk stronger than Kevlar
Spider silk is strong and tough, but hard to farm. Silkworm silk is easy to farm, but not that strong. What if we could combine the two?
Rare mutation may counteract “Alzheimer’s gene”
A rare mutation suggests that using CRISPR to reduce the expression of the APOE-e4 gene could help treat or prevent Alzheimer’s.
New CRISPR tool has an “on/off” switch
By splitting a base editor into two parts, researchers could give it an “on/off” switch that appears to make it safer and more effective.
Arrays of quantum rods could enhance TVs or virtual reality devices
MIT engineers have used DNA origami scaffolds to create structured arrays of quantum rods, which could be incorporated into LEDs.
One-shot gene therapy for liver disorder works in a small trial
A new gene therapy for the rare liver disorder Crigler-Najjar syndrome was highly effective in a small trial.
Extreme treatment for alcoholism slashes drinking by 90% in monkeys
An in-development treatment for alcoholism dramatically reduced consumption in monkeys that previously drank heavily.
Fragile X syndrome often results from improperly processed genetic material
Researchers discovered that the mutated gene responsible for fragile X syndrome is active in most people with the disorder, not silenced.
New study shows how electricity can turn on genes
A prototype wearable demonstrates a novel way to trigger gene expression: by zapping cells with electricity.