Studies show that loss of sleep can lead to memory loss, compromised immunity, weight gain, and mood swings. However, scientists are now finding that sleep deprivation may be used to treat depression. Losing sleep has the opposite effect on those struggling with depression. It restores the circadian rhythm that is usually flat in depressed people and it helps balance the parts of the brain that regulate mood. Unfortunately, the positive effects are immediately reversed when the patient goes to sleep. However, when combined with a lithium supplement and light therapy, lasting improvements can be achieved.